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RESEARCH ARTICLE

Edible Sulfonated Soy Protein Microcarriers for Cultivated Meat Cell Expansion.

Researchers developed edible microcarriers from soy protein isolate by chemically adding sulfonate groups, then assessed material properties, growth-factor adsorption and muscle-cell behavior. Sulfonation increased electrical conductivity and water absorption. Myoblasts attached to modified and unmodified soy gels without serum through an integrin β1-dependent mechanism. After 24 hours, modified carriers held 17 times more basic fibroblast growth factor than untreated soy carriers. They also supported faster early proliferation of primary bovine satellite cells than Cytodex 3 and maintained cell expansion for five days.

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