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Induced Pluripotent Stem Cells in Non-Model Species: Applications and Challenges.

Cells · 3 October 2026 · DOI 10.3390/cells15171565

Induced pluripotent stem cells in non-model species remain limited, constraining their use in conservation, medicine, farming and toxicology. The review compares progress across reprogramming, genetic rescue, laboratory gamete production, de-extinction, one-medicine research, disease resistance, climate resilience, cultivated meat and species-specific toxicity models. Shared vertebrate pluripotency machinery supports wider reprogramming in principle. Yet poor genome annotation, scarce validated reagents, weak culture systems and biological differences remain barriers. Evidence for more distant taxa remains thin, so broad application is still aspirational.

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Science digest

Alternative Proteins on the Polish Plate: Consumer Acceptance, Current Challenges, and Future Perspectives.

A narrative review examines Polish consumers’ views of five alternative protein categories, revealing uneven acceptance that may slow a shift towards more sustainable diets. Plant-based substitutes are furthest established, though cost, taste, nutrition doubts and processing concerns remain barriers. Cultivated meat draws middling support amid unfamiliarity and worries about safety and artificiality. Insects rank lowest because of disgust, food neophobia and cultural norms. Evidence for microalgae and mycoprotein is limited, while fermentation-derived proteins remain largely unstudied. Poland needs product-specific research and culturally apt communication.

3 October 2026

Science digest

Ethics of Cultured Meat - A Systematic Philosophical Approach to Assessing the Ethics of your future cultured meat

Cultured meat’s ethics depend on how it is made and what it replaces, making broad moral verdicts unreliable. The paper compares philosophical arguments with full production-process models and proposes a common assessment framework covering claims, basic protections, gains over alternatives, distribution, public justification and ongoing review. Different ethical theories keep their own tests rather than yielding one score. Some systems may beat intensive livestock, subject to strict sourcing, inputs, safety, energy and governance conditions. Plant-based or microbial foods may still fare better.

3 October 2026

Science digest

Quinoa and Peanut Extracts as Alternatives to Animal-Derived Extracellular Matrix Proteins in Cultured Meat Production.

Peanut and quinoa extracts supported muscle-cell growth much like animal-derived matrix proteins, suggesting a plant-based coating option for cultivated meat. Researchers screened edible plant proteins by computer for cell-binding RGD sequences, then tested water-soluble seed extracts on mouse C2C12 cells and immortalised bovine satellite cells. Coated surfaces enabled similar attachment and proliferation to animal-derived controls. Mass spectrometry found RGD-bearing proteins, while cell-free production tests linked one protein from each crop to increased attachment and growth. The evidence supports further work on animal-free surface coatings.

3 October 2026