Editor

REVIEW

Scalable Scaffold Materials for Structured Cultivated Meat.

A review assesses scaffold materials and manufacturing methods for structured cultivated meat, focusing on whether they can meet food-sector demands for edibility, low cost and scale. The authors compare synthetic, animal, plant, fungal, microbial and waste-derived materials for cell compatibility and production potential. They classify fabrication methods by their roles in cell growth, alignment, bulk form and multi-material assembly, with mass transport as a shared limit. Their central judgement is that tissue architecture, throughput and cost matter more commercially than replicating full muscle physiology.

Read the paper →

Related

Science digest

Induced Pluripotent Stem Cells in Non-Model Species: Applications and Challenges.

Induced pluripotent stem cells in non-model species remain limited, constraining their use in conservation, medicine, farming and toxicology. The review compares progress across reprogramming, genetic rescue, laboratory gamete production, de-extinction, one-medicine research, disease resistance, climate resilience, cultivated meat and species-specific toxicity models. Shared vertebrate pluripotency machinery supports wider reprogramming in principle. Yet poor genome annotation, scarce validated reagents, weak culture systems and biological differences remain barriers. Evidence for more distant taxa remains thin, so broad application is still aspirational.

Science digest

Highly Sustainable Plant and Yeast Hydrolysate-Based Alternative for Basal Medium Supports Long-Term In Vitro Propagation of Bovine Satellite Cells.

A basal medium made from partly digested plant and yeast biomass supported bovine satellite cell growth and differentiation, which matters because media add cost and environmental burdens to cultivated meat production. Researchers compared the hydrolysate formulation with a fully defined chemical medium, then used life-cycle assessment to estimate the effects of substitution. Proliferation and differentiation were comparable in both media. The assessment indicated lower potential environmental impacts. Basal-medium design therefore deserves as much scrutiny as protein supplements.

Science digest

Quinoa and Peanut Extracts as Alternatives to Animal-Derived Extracellular Matrix Proteins in Cultured Meat Production.

Peanut and quinoa extracts supported muscle-cell growth much like animal-derived matrix proteins, suggesting a plant-based coating option for cultivated meat. Researchers screened edible plant proteins by computer for cell-binding RGD sequences, then tested water-soluble seed extracts on mouse C2C12 cells and immortalised bovine satellite cells. Coated surfaces enabled similar attachment and proliferation to animal-derived controls. Mass spectrometry found RGD-bearing proteins, while cell-free production tests linked one protein from each crop to increased attachment and growth. The evidence supports further work on animal-free surface coatings.